UCR

Molecular, Cell and Systems Biology



Dmitri Maslov


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Office: (951) 827-6485
Fax:
1352E Spieth Hall
Office Hours: , 2pm - 3pm
Email: maslov@ucr.edu

Dmitri Maslov, Professor

Ph.D., Moscow University, 1984

Biography

Dr.  Maslov studies mitochondrial gene expression in Trypanosoma and Leishmania. These organisms belong to trypanosomatid protists some of which cause serious tropical diseases. Trypanosomatids, representing a highly divergent eukaryotic lineage, possess unique mechanisms of mitochondrial gene organization and expression including kinetoplast DNA networks, RNA editing, and an unusual system of translation. The current focus of Dr. Maslov's research is on the interface of RNA editing and translation, including mechanisms of edited mRNA recognition by the mitochondrial ribosomes. The other research area is biodiversity, phylogeny and evolution of parasitism in trypanosomatid protozoa. Dr.  Maslov participates in Cell, Molecular and Developmental Biology and Genetics, Genomics and Bioinformatics graduate programs.

Publications

  • Zhang, X., Lai, M., Chang, W., Yu, I., Ding, K., Mrazek, J., Ng, H., Yang, O., Maslov, D., and Zhou, H. (2016) Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing the leishmanial and human ribosomes. Nature Communications, 18;7:13223. doi: 10.1038/ncomms13223.
  • Aphasizheva, I., Maslov D.A., Qian, Y, Wang, Q., Costello, C.E., Aphasizhev, R. (2016) Ribosome-associated PPR proteins function as translational activators in mitochondria of trypanosomes. Mol. Microbiol, 99(6):1043-58.
  • Kozminsky, E., Kraeva, N., Ishemgulova, A., Dobakova, E., Lukes, J., Kment, P., Yurchenko, V., Votypka, J., Maslov, D. A. (2015) Host-specificity of monoxenous trypanosomatids: statistical analysis of the distribution and transmission patterns of the parasites from Neotropical Heteroptera. Protist, 166:551-568.
  • Skodova-Sverakova, I., Horvath, A., Maslov, D. A. (2015) Identification of the mitochondrially encoded subunit 6 of F1FO ATPase in Trypanosoma brucei. Mol. Biochem. Parasitol., 201:135-138.
  • Ridlon, L., Skodova, I., Pan, S., Lukes, J., Maslov, D. A. (2013) The Importance of the 45S Ribosomal Small Subunit-related Complex for Mitochondrial Translation in Trypanosoma brucei.J Biol Chem, 288(46): 32963-32978.
  • Aphasizheva, I., Maslov, D., Aphasizhev, R. (2013) Kinetoplast DNA-encoded ribosomal protein S12: a possible functional link between mitochondrial RNA editing and translation in Trypanosoma brucei. RNA Biol.,10(11): 1679-1688.
  • Votypka, J., Klepetkova, H., Yurchenko, V. Y., Horak, A., Lukes, J., Maslov, D.A. (2012)Cosmopolitan distribution of a trypanosomatid Leptomonas pyrrhocoris. Protist, 163, 616-631.
  • Sharma, M. R., Booth, T. M., Simpson, L., Maslov, D. A., Agrawal, R. K. (2009) Structure of a mitochondrial ribosome with minimal RNA. PNAS, 106:9637-9642.

For a complete publication list, click here.

Recent teaching....

  • Biology 005A, Introductory Cell and Molecular Biology
  • Biology 102, Introductory Genetics
  • Biology 119, Introductory Genomics and Bioinformatics
  • Biology 158, Medical Molecular Parasitology
  • Biology 201, Cell, Molecular, and Developmental Biology (graduate)

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Molecular, Cell and Systems Biology
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Manuela Martins-Green: Chair of Molecular, Cell and Systems Biology
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